Genetic conditions (Germline genetic disease) Involved chromosomal sites

• 5q21 is the location of the APC mutation that predisposes for FAP.

• 11p13 is the site of the WT-1 tumor gene

• 13q14 is the site of the RB retinoblastoma gene.

• 17q11 is the site of the NF-1 neurofibromatosis gene,

• 22q12 is the site of the NF-2 neurofibromatosis gene.