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Pathogenesis of Disseminated Intravascular Coagulation (DIC)

  • Consumptive Coagulopathy
  • Widespread coagulation leading to thrombin formation all over body and consumption of all platelets and coagulation factors.
  • Everything is consumed, and there are thrombi all over body.
  • Bleeding and vessel occlusion at the same time


  • Which LAB parameters will be abnormal???
  • All that you can think of….
  • Bleeding time, PT, aPTT, D-dimer, Fibrin Split Products
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