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Vascular and immunologic manifestations of infective endocarditis

Vascular & immunologic manifestations of infective endocarditis:

Duke Criteria

Vascular phenomena:

  • Systemic arterial emboli (focal neurologic deficits, renal or splenic infarcts)
  • Septic pulmonary infarcts
  • Mycotic aneurysm
  • Conjunctival hemorrhages
  • Janeway lesions- Macular, erythematous, non-tender lesions on the palms and soles.

Immunologic phenomena:
  • Osler's nodes- Painful, violaceous nodules seen on the fingertips & toes.
  • Roth spots- Edematous and hemorrhagic lesions of the retina.
  • Glomerulonephritis
  • Arthritis or positive rheumatoid factor.

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