Myocarditis Etiology
Viral – Coxsackie A, ECHO, Influenza, Entero,
HIV, Adeno, CMV
Chlamydia and Rickettsia
Bacteria – diphtheria, Neisseria, Borrelia
Protozoa – Trypanosoma, Toxoplasma, Trichinella
Hypersensitivity – SLE( Libman Sacks endocarditis), RHD, graft rejection
Drugs: doxorubicin
Physical Agents – Radiation
Idiopathic – Giant cell myocarditis
Myocarditis Morphology
Gross –dilated, flabby heart, pale patches with hemorrhage giving mottled appearance, abscess if bacterial
Microscopic – interstitial inflammatory infiltrate with myocyte necrosis, fibrosis, viral inclusion bodies
Mononuclear cells – idiopathic or viral
Neutrophils – bacterial
Eosinophils –hypersensitivity or protozoa
Granulomatous – TB or sarcoid
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEigyvqXi7mwlA1wkS92CNJOs78-6BpdsadQtLVGKQ-k58ufB0gdnmHM4oYRLPqhfLkSV47gMVtkWmGiayXo7h1ss-Mrf92TWuBH9SbfIfxHPLlxrnNDw21EpleCUp3Slw0ws37EIEmbXJA/s320/Dilated%252C+globoid+Heart.png)
Dilated, globoid
heart in
myocarditis
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiuB8dYcYry-FhNHJUqKJCJCOPAQQ5qdt5u18Rjzzdn5NP89EWvEHoh_1Ho5GxwymmcudXmisjPuIf15JG-iKb5PAzsiIEQdv4JbDRAH23fRs5Z-zkEPd5laJxDTExsAfNWlf1LP3RFSUY/s320/Bacterial+colony+in+myocarditis.png)
Bacterial colony in myocarditis
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiQBsrLNkWufFgAGIBIMEHmxohqqhmz1hCRNEogPI0osbUYLfjGvB0oKUPlquRcao8fN_MOUp2jZxdNW7GmSMKp8SdfCEQJHrBOuBf863y_E8H7wiGbT-VD-ZvQl3hSx_geDXgfe5OOhq8/s320/Toxoplasmosis.png)
Toxoplasmosis
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEheLJ2AIwb70cmdGlqrblUlh7Ox_t7NQZUH0fgbzhhf2eyhjKy557WoH2D0cB9-B3I55khF4gshhQ74069OguepY821cFJ6GlGABJLLm-w5VMFA47rKToVyjQoh_swsSlDCPKptAoBNQ2c/s320/Chagas+disease.png)
Chagas disease
Intrstng gud collection of slids :)
ReplyDelete