Clinical features of Viral Hepatitis....(b)

Some patients with acute hepatitis B develop a serum sickness-like syndrome consisting of fever, rash, and arthralgias, nephritis, attributed to circulating immune complexes

higher fever, shaking chills, and headache, sometimes accompanied by right upper quadrant pain and tender liver enlargement

conjugated hyperbilirubinemia: dark-colored urine related to the presence of conjugated bilirubin. Later unconjugated hyperbilirubinemia can also occur

The stools may become light colored due to cholestasis, and the retention of bile salts may cause distressing pruritus

Chronic hepatitis is defined as ongoing inflammation for more than 6 months, with histologically documented inflammation and necrosis

The Carrier State : vertical transmission during childbirth, produces a carrier state 90% to 95% of the time. In contrast, only 1% to 10% of HBV infections acquired in adulthood

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