Primary
Secondary: chronic hepatitis B, syphilis, schistosomiasis, malaria, lung and colon cancer, melanoma; SLE, gold, mercury, penicillamine, captopril, NSAIDs
diffuse thickening of the GBM
effacement of foot processes
Immunofluorescence microscopy shows typical granular deposits of immunoglobulins and complement along the GBM
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhmdtZjwooU3YChr78lqUwS_xomKnTTlZa43q22YhRurRrFEcY6i-M79DwsTl8jHyF6Z7QVkaQsIbAPQqKBKHeAr47hBVhSaU5_hQ2b0nrYrow_seek5zEobMZGtCT9IUnBdXnUw3BUPWiS/s320/Membranous+GN.png)
Membranous glomerulonephritis. A, PAS stain. Note the marked diffuse thickening of the capillary wall without an increase in the number of cells.
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